Flow-controlled ventilation (FCV)
of ARDS patients using Evone – Supporting evidence
CLINICAL EXPERIENCE
Summary:
- 22 year old male patient with traumatic brain injury and chest trauma admitted to ICU; P/F ratio 49 mmHg
- Conventional strategies (VCV and lateral rotational therapy) did not improve respiratory parameters; ECMO was contraindicated
- FCV was started and settings were individually optimized
- Significant lung improvement within few hours: P/F ratio 177, 270 and 397 mmHg after 1, 12 and 24 hours, respectively
- Chest radiographs showed improved lung condition
- Patient entered weaning procedure after in total 77 hours FCV ventilation
- Discharged two weeks later in favorable condition
Publication:
Bergold et al. WAMM 2019. Flow-controlled ventilation: A novel approach to treating severe acute respiratory distress syndrome. Link to e-poster: https://epostersonline.com/wamm2019/node/1498?view=true
Day 1
Day 3
CLINICAL EXPERIENCE
Summary:
- 3 hours of FCV compared to VCV, with similar PEEP, Peak, tidal volume and respiratory rate
- FCV improved oxygenation by 47% while using a 26% lower minute volume
- FCV showed decreased signs of alveolar lung damage
- FCV resulted in significantly more normally aerated and less non-aerated lung tissue compared to VCV
Publication:
Schmidt et al. Flow-Controlled Ventilation Attenuates Lung Injury in a Porcine Model of Acute Respiratory Distress Syndrome: A Preclinical Randomized Controlled Study. Crit Care Med 2020; 48:e241–e248. Link to full publication: https://journals.lww.com/ccmjournal/Fulltext/2020/03000/Flow_Controlled_Ventilation_Attenuates_Lung_Injury.36.aspx
Randomized controlled study: FCV showed superior ventilation to PCV in porcine ARDS
- FCV was individually optimized based on compliance
- Manuscript currently in preparation
BACKGROUND
- Safety and performance of FCV for ventilation of lung-healthy patients demonstrated in observational and randomised controlled studies
- FCV provides higher efficient ventilation, more homogenous lung recruitment, better lung aeration, and ventilation with lower energy dissipation than VCV or PCV
- For details and links to all publications see http://ventinovamedical.com/literature/
LATEST NEWS
Symposium organized by Erasmus Medical Center
Erasmus Medical Center (Rotterdam, the Netherlands) is organizing a hybrid symposium on Flow Controlled Ventilation blowing away VILI.The event will be held on the 28th of October in Rotterdam but can also be watched online.For more information click...
SIGN UP FOR OUR NEWSLETTER:
CONTACT US
Ventinova Medical
Meerenakkerplein 7
5652 BJ Eindhoven (NL)
T. +31 649 998 203
T. +34 944 008 847 ( IES Medical )
Chamber of Commerce: 58307834